dexmedetomidine

Ligand Id: 521
Ligand name dexmedetomidine

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 28.68
Molecular weight 200.13
XLogP 4.6
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1999))
IUPAC Name
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-3H-imidazole
International Nonproprietary Names
INN number INN
6277 dexmedetomidine
Synonyms
MPV 1440
Precedex®
Database Links
BindingDB Ligand 50241196
CAS Registry No. 113775-47-6 (source: Scifinder)
ChEBI CHEBI:4466
ChEMBL Ligand CHEMBL778
DrugBank Ligand DB00633
PharmGKB Drug PA449256
PubChem CID 5311068
Search Google for chemical match using the InChIKey CUHVIMMYOGQXCV-NSHDSACASA-N
Search Google for chemicals with the same backbone CUHVIMMYOGQXCV
Search PubMed clinical trials dexmedetomidine
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Wikipedia Dexmedetomidine
Comments
Dexmedetomidine is a somewhat selective α2-adrenoceptor agonist with sedative properties.