milrinone

Ligand id: 5225

Name: milrinone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 65.78
Molecular weight 211.07
XLogP 1.25
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1987))
IUPAC Name
6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridine-3-carbonitrile
International Nonproprietary Names
INN number INN
5383 milrinone
Synonyms
milrinone lactate | Primacor®
Database Links
CAS Registry No. 78415-72-2
ChEBI CHEBI:50693
ChEMBL Ligand CHEMBL189
DrugBank Ligand DB00235
GtoPdb PubChem SID 178101910
PubChem CID 4197
RCSB PDB Ligand MIL
Search Google for chemical match using the InChIKey PZRHRDRVRGEVNW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone PZRHRDRVRGEVNW
Search PubMed clinical trials milrinone
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Search UniChem for chemical match using the InChIKey PZRHRDRVRGEVNW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone PZRHRDRVRGEVNW
Wikipedia Milrinone
Comments
Milrinone is a phosphodiesterase 3 (PDE3) inhibitor.