lifibrol

Ligand id: 5885

Name: lifibrol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 66.76
Molecular weight 342.18
XLogP 7.18
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[4-(4-tert-butylphenyl)-2-hydroxybutoxy]benzoic acid
International Nonproprietary Names
INN number INN
6470 lifibrol
Synonyms
K 12148 | K12.148 | U-83860
Database Links
CAS Registry No. 96609-16-4 (source: Scifinder)
ChEMBL Ligand CHEMBL2105019
PubChem CID 57112
Search Google for chemical match using the InChIKey LNXBEIZREVRNTF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone LNXBEIZREVRNTF
Search PubMed clinical trials lifibrol
Search PubMed titles lifibrol
Search PubMed titles/abstracts lifibrol
Search UniChem for chemical match using the InChIKey LNXBEIZREVRNTF-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone LNXBEIZREVRNTF
Comments
Lifibrol is a model compound being investigated in the development of novel pharmacotherapies for dyslipidaemia [1]. The compoound appears to be a cholesterol synthesis inhibitor.
The INN document for lifibrol specifies that it is a racemic mixture of two enatiomers. We do not specify stereochemistry in our structure therefore this entry represents the mixture.