zofenopril

Ligand id: 6462

Name: zofenopril

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 125.28
Molecular weight 429.11
XLogP 5.75
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
Is prodrug? Yes
Active form zofenoprilat
IUPAC Name
(2S,4S)-1-[(2S)-3-(benzoylsulfanyl)-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylic acid
International Nonproprietary Names
INN number INN
5535 zofenopril
Synonyms
SO-26991 | SQ-26900
Comments
Metabolised to the active from zofenoprilat. The United States Adopted Name (USAN) for this compound is zofenopril calcium (PubChem CID 3033690).
Database Links
CAS Registry No. 81872-10-8 (source: PubChem)
ChEMBL Ligand CHEMBL331378
GtoPdb PubChem SID 178103076
PubChem CID 92400
Search Google for chemical match using the InChIKey IAIDUHCBNLFXEF-MNEFBYGVSA-N
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Search UniChem for chemical match using the InChIKey IAIDUHCBNLFXEF-MNEFBYGVSA-N
Search UniChem for chemicals with the same backbone IAIDUHCBNLFXEF
Wikipedia Zofenopril