moexipril

Ligand id: 6571

Name: moexipril

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 13
Topological polar surface area 114.4
Molecular weight 498.24
XLogP 4.86
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1995))
Is prodrug? Yes
Active form moexiprilat
IUPAC Name
(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
International Nonproprietary Names
INN number INN
6266 moexipril
Synonyms
RS-10085 | SPM-925 | Univasc®
Comments
ACE inhibitor prodrug metabolised to moexiprilat. This compound has hydrochloride database entries such as CID 54889 and nine isomers in PubChem.
Database Links
CAS Registry No. 103775-10-6 (source: Scifinder)
ChEMBL Ligand CHEMBL1165
DrugBank Ligand DB00691
GtoPdb PubChem SID 178103185
PubChem CID 91270
Search Google for chemical match using the InChIKey UWWDHYUMIORJTA-HSQYWUDLSA-N
Search Google for chemicals with the same backbone UWWDHYUMIORJTA
Search PubMed clinical trials moexipril
Search PubMed titles moexipril
Search PubMed titles/abstracts moexipril
Search UniChem for chemical match using the InChIKey UWWDHYUMIORJTA-HSQYWUDLSA-N
Search UniChem for chemicals with the same backbone UWWDHYUMIORJTA
Wikipedia Moexipril