moexipril

Ligand id: 6571

Name: moexipril

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View more information in the IUPHAR Pharmacology Education Project: moexipril

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 13
Topological polar surface area 114.4
Molecular weight 498.24
XLogP 4.86
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1995))
Is prodrug? Yes
Active form moexiprilat
IUPAC Name
(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
International Nonproprietary Names
INN number INN
6266 moexipril
Synonyms
RS-10085 | SPM-925 | Univasc®
Database Links
CAS Registry No. 103775-10-6 (source: Scifinder)
ChEMBL Ligand CHEMBL1165
DrugBank Ligand DB00691
PubChem CID 91270
Search Google for chemical match using the InChIKey UWWDHYUMIORJTA-HSQYWUDLSA-N
Search Google for chemicals with the same backbone UWWDHYUMIORJTA
Search PubMed clinical trials moexipril
Search PubMed titles moexipril
Search PubMed titles/abstracts moexipril
Search UniChem for chemical match using the InChIKey UWWDHYUMIORJTA-HSQYWUDLSA-N
Search UniChem for chemicals with the same backbone UWWDHYUMIORJTA
Wikipedia Moexipril
Comments
ACE inhibitor prodrug metabolised to moexiprilat. This compound has hydrochloride database entries such as CID 54889 and nine isomers in PubChem.