certolizumab pegol

Ligand id: 6774

Name: certolizumab pegol

Compound class Antibody
Approved drug? Yes (source: FDA (2008))
International Nonproprietary Names
INN number INN
8448 certolizumab pegol
PHA 738144
Database Links
Specialist databases
IMGT/mAb-DB 242
Other databases
PubChem SID 178103380
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Wikipedia Certolizumab_pegol
TNFα neutralising agent. This is a Fab' fragment of a TNFα-binding monoclonal antibody, which has polyethylene glycol (PEG) conjugated to a free cysteine residue in its hinge region (Cys227 of the heavy chain). PEGylation is used to increase the drug's half life, as Fab' fragments are normally rapidly degraded in vivo.