methylprednisolone

Ligand id: 7088

Name: methylprednisolone

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: methylprednisolone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 94.83
Molecular weight 374.21
XLogP 1.53
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
Approved drug? Yes (FDA (1957))
IUPAC Name
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
International Nonproprietary Names
INN number INN
732 methylprednisolone
Synonyms
Medrol® | U-67590A
Database Links
CAS Registry No. 83-43-2
ChEBI CHEBI:6888
ChEMBL Ligand CHEMBL650
DrugBank Ligand DB00959
GtoPdb PubChem SID 178103666
NURSA Ligand 10.1621/6A7WO8R4WE
PubChem CID 6741
Search Google for chemical match using the InChIKey VHRSUDSXCMQTMA-PJHHCJLFSA-N
Search Google for chemicals with the same backbone VHRSUDSXCMQTMA
Search PubMed clinical trials methylprednisolone
Search PubMed titles methylprednisolone
Search PubMed titles/abstracts methylprednisolone
Search UniChem for chemical match using the InChIKey VHRSUDSXCMQTMA-PJHHCJLFSA-N
Search UniChem for chemicals with the same backbone VHRSUDSXCMQTMA
Wikipedia Methylprednisolone
Comments
Methylprednisolone is a corticosteroid.
Marketed formulations may contain methylprednisolone acetate (PubChem CID 5877).