doxazosin

Ligand id: 7170

Name: doxazosin

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 96.35
Molecular weight 451.19
XLogP 1.93
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1990))
IUPAC Name
2-[4-(2,3-dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]-6,7-dimethoxy-3,4-dihydroquinazolin-4-imine
International Nonproprietary Names
INN number INN
5143 doxazosin
Synonyms
Cardura® | UK-3327427
Database Links
CAS Registry No. 74191-85-8
ChEMBL Ligand CHEMBL707
DrugBank Ligand DB00590
GtoPdb PubChem SID 178103745
PubChem CID 3157
Search Google for chemical match using the InChIKey RUZYUOTYCVRMRZ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone RUZYUOTYCVRMRZ
Search PubMed clinical trials doxazosin
Search PubMed titles doxazosin
Search PubMed titles/abstracts doxazosin
Search UniChem for chemical match using the InChIKey RUZYUOTYCVRMRZ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone RUZYUOTYCVRMRZ
Wikipedia Doxazosin
Comments
Doxazosin blocks α1-adrenoceptors.
Marketed formulations may contain doxazosin mesylate (PubChem CID 62978).