doxazosin

Ligand id: 7170

Name: doxazosin

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 96.35
Molecular weight 451.19
XLogP 1.93
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Hancock AA, Buckner SA, Brune ME, Katwala S, Milicic I, Ireland LM, Morse PA, Knepper SM, Meyer MD,Chapple CR et al.. (1998)
Pharmacological characterization of A-131701, a novel R 1 -adrenoceptor antagonist selective for R 1A - and R 1D - compared to R 1B -adrenoceptors.
Drug Development Research44: 140-162.