lansoprazole

Ligand id: 7208

Name: lansoprazole

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View more information in the IUPHAR Pharmacology Education Project: lansoprazole

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 87.08
Molecular weight 369.08
XLogP 2.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1995))
IUPAC Name
2-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole
International Nonproprietary Names
INN number INN
6397 lansoprazole
Synonyms
A-65006 | AG-1749 | Prevacid®
Database Links
CAS Registry No. 103577-45-3
ChEMBL Ligand CHEMBL480
DrugBank Ligand DB00448
GtoPdb PubChem SID 178103783
PubChem CID 3883
Search Google for chemical match using the InChIKey MJIHNNLFOKEZEW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone MJIHNNLFOKEZEW
Search PubMed clinical trials lansoprazole
Search PubMed titles lansoprazole
Search PubMed titles/abstracts lansoprazole
Search UniChem for chemical match using the InChIKey MJIHNNLFOKEZEW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone MJIHNNLFOKEZEW
Wikipedia lansoprazole
Comments
Lansoprazole is a proton pump inhibitor drug. The approved drug is a racemic mixture of chemical enantiomers; (S)-lansoprazole and dexlansoprazole. We show the non-stereoisomeric molecule to represent this mixture.