rabeprazole

Ligand id: 7290

Name: rabeprazole

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 96.31
Molecular weight 359.13
XLogP 1.49
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1999))
IUPAC Name
2-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole
International Nonproprietary Names
INN number INN
7112 rabeprazole
Synonyms
AcipHex® | E-3810 | Pariet®
Comments
Rabeprazole is a proton pump inhibitor. This compound is a prodrug which is converted into the active sulphenamide form in the acid environment of the parietal cells.
Marketed formulations may contain rabeprazole sodium (PubChem CID 14720269).
Database Links
CAS Registry No. 17976-89-3
ChEMBL Ligand CHEMBL1219
DrugBank Ligand DB01129
GtoPdb PubChem SID 178103864
PubChem CID 5029
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Wikipedia Rabeprazole