AZD7325

Ligand id: 7712

Name: AZD7325

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 90.13
Molecular weight 354.15
XLogP 3.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide
Synonyms
AZD 7325 | AZD-7325
Comments
AZD7325 was developed as a positive allosteric modulator of the GABAA α2 and α3 channels and was investigated as a treatment for generalised anxiety disorder. This compound is now included in AstaZeneca's Open Innovation Pharmacology Toolbox.
Database Links
ChEMBL Ligand CHEMBL1783282
GtoPdb PubChem SID 223366045
PubChem CID 23581869
Search Google for chemical match using the InChIKey KYDURMHFWXCKMW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone KYDURMHFWXCKMW
Search UniChem for chemical match using the InChIKey KYDURMHFWXCKMW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone KYDURMHFWXCKMW