Classification
Compound class	Synthetic organic

IUPAC Name

8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid

International Nonproprietary Names
INN number	INN
9891	bempedoic acid

Synonyms

ESP-55016 | ETC-1002

Comments

Bempedoic acid is a novel investigational drug being developed for the treatment of dyslipidemia and related cardiovascular disease. Functionally the compound acts as an inhibitor of ATP citrate lyase (ACLY; P53396), which is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, which in turn is required for de novo lipogenesis and cholesterogenesis.

Database Links
CAS Registry No.	738606-46-7
ChEMBL Ligand	CHEMBL3545313
GtoPdb PubChem SID	252166533
PubChem CID	10472693
Search Google for chemical match using the InChIKey	HYHMLYSLQUKXKP-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey	HYHMLYSLQUKXKP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	HYHMLYSLQUKXKP