IFN-β1b (recombinant human)

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Ligands
IFN-β1b (recombinant human)

Ligand id: 8340

Name: IFN-β1b (recombinant human)

Summary
Biological activity
Clinical data
References
Structure
Similar ligands
Immunopharmacology

Classification
Compound class	Peptide or derivative
Approved drug?	Yes (source: FDA (1993))

International Nonproprietary Names
INN number	INN
5380	interferon beta

Synonyms
Betaferon®
Betaseron®
Extavia®
IFNb1b

Synonyms

Betaferon®

Betaseron®

Extavia®

IFNb1b

Database Links
Specialist databases
IMGT/mAb-DB	641
Other databases
DrugBank Ligand	DB00068
Search PubMed clinical trials	interferon beta
Search PubMed titles	interferon beta
Search PubMed titles/abstracts	interferon beta
Wikipedia	Interferon_beta_1b

Comments
Compared to the sequence of endogenous IFN-β, IFN-β1b has a Ser to Cys substitution at position 17, but does not retain the glycosylation site at Asn80. It also lacks the initiating Met. This recombinant peptide is produced in E.coli.

Comments

Compared to the sequence of endogenous IFN-β, IFN-β1b has a Ser to Cys substitution at position 17, but does not retain the glycosylation site at Asn80. It also lacks the initiating Met. This recombinant peptide is produced in E.coli.