IFN-β1b (recombinant human)

Ligand id: 8340

Name: IFN-β1b (recombinant human)

Classification
Compound class Peptide or derivative
Approved drug? Yes (FDA (1993))
International Nonproprietary Names
INN number INN
5380 interferon beta
Synonyms
Betaferon® | Betaseron® | Extavia® | IFNb1b
Database Links
Specialist databases
IMGT/mAb-DB 641
Other databases
DrugBank Ligand DB00068
Search PubMed clinical trials interferon beta
Search PubMed titles interferon beta
Search PubMed titles/abstracts interferon beta
Wikipedia Interferon_beta_1b
Comments
Compared to the sequence of endogenous IFN-β, IFN-β1b has a Ser to Cys substitution at position 17, but does not retain the glycosylation site at Asn80. It also lacks the initiating Met. This recombinant peptide is produced in E.coli.