|
Synonyms: Betaferon® | Betaseron® | Extavia® | IFNb1b
IFN-β1b (recombinant human) is an approved drug (FDA (1993), EMA (1995))
Compound class:
Peptide or derivative
Comment: Compared to the sequence of endogenous IFN-β, IFN-β1b has a Ser to Cys substitution at position 17, but does not retain the glycosylation site at Asn80. It also lacks the initiating Met. This recombinant peptide is produced in E.coli.
|
| Immunopharmacology Disease | |||
| Disease | X-Refs | Comment | References |
| Multiple sclerosis |
Disease Ontology:
DOID:2377 OMIM: 126200 Orphanet: ORPHA802 |
Approved drug for relapsing forms of MS. | |
