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Molecular properties generated using the CDK
|Compound class||Synthetic organic|
|example 362 [WO2010074588]||2|
|Search Google for chemical match using the InChIKey||DOWVMJFBDGWVML-UHFFFAOYSA-N|
|Search Google for chemicals with the same backbone||DOWVMJFBDGWVML|
|BIA 10-2474 is a reversible inhibitor of fatty acid amide hydrolase (FAAH) at the heart of a disaterous clinical trial in France which left one participant dead and several others with possibly permanent brain damage. The compound is claimed in patent WO2010074588 .
The structure of BIA 10-2474 was disclosed in a clinical trial protocol with EudraCT No: 2015-001799-24.
Pharmacologic inhibition of FAAH is being investigated in the search for novel analgesic drugs [3-5].
More information surrounding this compound and its unfortunate clinical trial outcome is available in two blogposts by our curator Christopher Southan (The unfortunate case of BIA-10-2474 and Molecular details related to BIA 10-2474)