deflazacort

Ligand id: 9477

Name: deflazacort

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View more information in the IUPHAR Pharmacology Education Project: deflazacort

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 102.26
Molecular weight 441.22
XLogP 1.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
Synonyms
Emflaza® | MDL 458
Database Links
GtoPdb PubChem SID 329968417
PubChem CID 189821
Search Google for chemical match using the InChIKey FBHSPRKOSMHSIF-GRMWVWQJSA-N
Search Google for chemicals with the same backbone FBHSPRKOSMHSIF
Search UniChem for chemical match using the InChIKey FBHSPRKOSMHSIF-GRMWVWQJSA-N
Search UniChem for chemicals with the same backbone FBHSPRKOSMHSIF
Comments
A glucocorticoid used as an anti-inflammatory and immunosuppressant. This is a prodrug which is metabolised to the active form, 21-desacetyl deflazacort (PubChem CID 97547130) [3].