Synonyms: prontosil red | prontosil rubrum | sulfamidochrysoidine
Compound class:
Synthetic organic
Comment: Prontosil is a sulfonamide antibacterial compound and the first drug available commercially for the treatment of bacterial infections. It is a prodrug of sulfanilamide. The antibacterial properties of prontosil were first identified by Gerhard Domagk (Bayer Laboratories) in the early 1930s, leading to him being awarded the 1939 Nobel Prize in Physiology or Medicine [5].
|
|
Bioactivity Comments |
The sulfonamide class of antibacterial compounds are primarily bacteriostatic. Prontosil demonstrates in vivo activity against Streptococcus spp [3-4]. |