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Synonyms: NX-210 | NX-210c | NX210c | SCO-spondin derived peptide NX210
Compound class:
Peptide or derivative
Comment: NX210 is a synthetic dodecapeptide that was developed for neuroprotective and neuroregenerative properties [3]. Its amino acid sequence is derived from the thrombospondin type 1 repeat of the neuronal differentiation protein subcommissural organ (SCO)-spondin [2]. Structurally the peptide can establish a cyclic formation through generation of an intrachain disulfide bridge between the two cysteine residues (then referred to as NX210c).
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| Bioactivity Comments |
| NX210 dose-dependently increases neurite outgrowth of rat neuroblastoma cells in vitro [2]. |
