diquafosol

Ligand id: 1736

Name: diquafosol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 27
Hydrogen bond donors 10
Rotatable bonds 14
Topological polar surface area 432.79
Molecular weight 789.99
XLogP -9
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
P2Y2 receptor Agonist Full agonist 7.0 pEC50 - 2
pEC50 7.0 [2]
P2Y4 receptor Agonist Full agonist 6.4 pEC50 - 1
pEC50 6.4 [1]
Ligand mentioned in the following text fields