beraprost

Ligand id: 1967

Name: beraprost

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 86.99
Molecular weight 398.21
XLogP 3.43
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
IP receptor Mm Agonist Full agonist 7.8 pKi - 1
pKi 7.8 [1]
IP receptor Rn Agonist Agonist 7.7 pKi - 2
pKi 7.7 (Ki 1.9x10-8 M) [2]
IP receptor Hs Agonist Agonist 7.4 pKi - 2
pKi 7.4 (Ki 3.9x10-8 M) [2]
EP3 receptor Hs Agonist Agonist 6.2 pKi - 2
pKi 6.2 (Ki 6.8x10-7 M) [2]
EP4 receptor Hs Agonist Agonist 5.1 pKi - 2
pKi 5.1 (Ki 7.2x10-6 M) [2]