capeserod

Ligand id: 29

Name: capeserod

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 77.26
Molecular weight 456.16
XLogP 4.33
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
5-HT4 receptor Agonist Partial agonist 9.2 pKi - 1
pKi 9.2 [1]
5-HT1A receptor Agonist Partial agonist 6.0 pKi - 1
pKi 6.0 [1]
5-HT2A receptor Agonist Partial agonist 5.9 pKi - 1
pKi 5.9 [1]
5-HT2B receptor Agonist Partial agonist 5.8 pKi - 1
pKi 5.8 [1]
5-HT6 receptor Agonist Partial agonist 5.6 pKi - 1
pKi 5.6 [1]
5-HT7 receptor Agonist Partial agonist 5.5 pKi - 1
pKi 5.5 [1]
5-HT1B receptor Agonist Partial agonist 5.3 pKi - 1
pKi 5.3 [1]
5-HT2C receptor Agonist Partial agonist 5.3 pKi - 1
pKi 5.3 [1]
5-HT1D receptor Agonist Partial agonist 5.1 pKi - 1
pKi 5.1 [1]