[D-Phe6, Leu13, Cpa14,ψ13-14]bombesin-(6-14)   Click here for help

GtoPdb Ligand ID: 3840

Synonyms: [D-Phe6,Cpa14,ψ13-14]bombesin6-14 | [D-Phe6,Leu13,Cpa14,ψ13-14]bombesin-(6-14) | analogue #7 [PMID: 19463875]
Comment: Synthetic analogue of bombesin [1].
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Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
BB2 receptor Primary target of this compound Hs Antagonist Antagonist 9.8 pKi - 1
pKi 9.8 [1]
BB2 receptor Rn Antagonist Antagonist 7.4 pKi - 2
pKi 7.4 (Ki 4.2x10-8 M) [2]
BB2 receptor Hs Antagonist Antagonist 8.9 – 8.9 pIC50 - 1
pIC50 8.9 – 8.9 (IC50 1.35x10-9 – 1.23x10-9 M) [1]
BB1 receptor Hs Antagonist Antagonist <5.0 pIC50 - 1
pIC50 <5.0 (IC50 >1x10-5 M) [1]