[125I]AB-MECA

Ligand id: 436

Name: [125I]AB-MECA    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 5
Rotatable bonds 6
Topological polar surface area 160.44
Molecular weight 525.06
XLogP 0.84
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
A3 receptor Agonist Full agonist 9.0 – 9.1 pKd - 2-3
pKd 9.0 – 9.1 (Kd 1x10-9 – 6x10-10 M) [2-3]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
A3 receptor Agonist Full agonist 8.9 pKd - 1
pKd 8.9 [1]
Ligand mentioned in the following text fields