AG 1295

Ligand id: 5914

Name: AG 1295

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 25.78
Molecular weight 234.12
XLogP 5.43
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
AG 1295 inhibits in vitro autophosphorylation of mouse PDGFR with an IC50 of 300-500nM [3].