Akt inhibitor IV

Ligand id: 5919

Name: Akt inhibitor IV

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 53.18
Molecular weight 487.2
XLogP 10.11
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
This compound completely abolishes phosphorylation of Ser473 of AKT in human 786-O adenocarcinoma cells [4].
We have been unable to find a publicly available activity valus for this compound at AKT or any other proposed molecular target.