Bcr-abl inhibitor GNF-2

Ligand id: 5935

Name: Bcr-abl inhibitor GNF-2

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 90.13
Molecular weight 374.1
XLogP 4.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
This compound inhibits the Bcr/Abl fusion protein with an IC50 value of 267nM [1].