compound 26 [PMID: 16439120]

Ligand id: 6372

Name: compound 26 [PMID: 16439120]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 58.8
Molecular weight 259.05
XLogP 2.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at rat GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
mGlu5 receptor Allosteric modulator Negative 8.0 pKi - 1
pKi 8.0 (Ki 1x10-8 M) [1]