Ligand id: 6477

Name: mogamulizumab

Bioactivity Comments
Peptide sequence analysis of the heavy chain variable region of mogamulizumab matches sequence ID 9 from patent US7504104 [2], linking this antibody with clones Gal1LV1, Gal1LV2 or Gal1LV3. A graph of CCR4 binding by these antibody clones is provided in the patent, but no affinity value is specified.
Selectivity at GPCRs
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Target Sp. Type Action Affinity Units Concentration range (M) Reference
CCR4 Hs Antibody Inhibition - - - 1-2