fasidotrilat

Ligand id: 6502

Name: fasidotrilat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 123.66
Molecular weight 311.08
XLogP 1.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
Neutral endopeptidase Hs Inhibitor Inhibition 8.3 pKi - 2
pKi 8.3 (Ki 5.6x10-9 M) [2]
Angiotensin-converting enzyme Hs Inhibitor Inhibition 8.0 pKi - 1
pKi 8.0 (Ki 9.8x10-9 M) [1]