rituximab

Ligand id: 6780

Name: rituximab

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View more information in the IUPHAR Pharmacology Education Project: rituximab

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Bioactivity Comments
The patents covering rituximab do not contain any data regarding antibody-antigen affinity [2-3], but a dissociation constant is provided by Stein et al (2004) [6].
Selectivity at human other protein targets
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Target Type Action Affinity Units Concentration range (M) Reference
CD20 (membrane-spanning 4-domains, subfamily A, member 1) Antibody Binding 8.5 pKd - 6
pKd 8.5 (Kd 3.1x10-9 M) [6]