fondaparinux

Ligand id: 6819

Name: fondaparinux

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 52
Hydrogen bond donors 19
Rotatable bonds 30
Topological polar surface area 872.52
Molecular weight 1506.95
XLogP -18.67
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human other protein targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
serpin family C member 1 Activator Activation 7.5 pKd - 1
pKd 7.5 (Kd 3.2x10-8 M) [1]
Description: Catalyses the inactivation of coagulation proteases by activated antithrombin-III