Ligand id: 6882

Name: cetuximab

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Peptide sequence analysis matches the light chain variable region of cetuximab to patent US7060808 [1]. The Kd value provided in the interaction table below is taken from this patent for the C225 monoclonal presented therein.
Selectivity at human catalytic receptors
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Target Type Action Affinity Units Concentration range (M) Reference
epidermal growth factor receptor Antibody Binding 9.4 pKd - 1
pKd 9.4 (Kd 3.9x10-10 M) [1]