Ligand id: 6885

Name: ustekinumab

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
The patent covering the production and use of ustekinumab (US6902734 [1]) does not provide affinity values for specific antibody clones, therefore we have included the stated range of affinities determined in the production and testing process in the interaction table below..
Selectivity at Human ligand targets
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Target Type Action Affinity Units Concentration range (M) Reference
IL-12B Antibody Inhibition >9.0 – 11.1 pKd - 1
pKd >9.0 – 11.1 (Kd <1x10-9 – 7x10-12 M) [1]