obinutuzumab

Ligand id: 6941

Name: obinutuzumab

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Bioactivity Comments
In vitro, obinutuzumab induces cell death and antibody-dependent cell-mediated cytotoxicity (ADCC) more effectively than the original type I anti-CD20 antibodies rituximab and ofatumumab [2]. In vivo, obinutuzumab induces a strong antitumour effect [2].
However, we have been unable to find affinity data for this antibody from any open access source.
Selectivity at human other protein targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
CD20 (membrane-spanning 4-domains, subfamily A, member 1) Antibody Binding - - - 1,3
[1,3]