anisindione

Ligand id: 6960

Name: anisindione

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 43.37
Molecular weight 252.08
XLogP 3.13
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
The majority of references for anisindione are very old and provide little in the way of molecular target validation. Although it is widely reported in various web and literature resources we have found no available, peer reviewed article to substantiate γ-glutamyl carboxylase as anisindione's primary molecular target .
Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
γ-Glutamyl carboxylase Inhibitor Inhibition - - -