azidopine

Ligand id: 6980

Name: azidopine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 13
Topological polar surface area 106.09
Molecular weight 557.19
XLogP 7.64
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human ion channels
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Target Type Action Affinity Units Concentration range (M) Reference
Cav1.3 Gating inhibitor Inhibition 9.2 pIC50 - 1
pIC50 9.2 (IC50 6.5x10-10 M) [1]
Description: Recombinant Cav1.3 calcium channel complexes expressed in tsA201-cells