sucralfate

Ligand id: 7055

Name: sucralfate

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 51
Hydrogen bond donors 16
Rotatable bonds 36
Topological polar surface area 839.21
Molecular weight 1447.59
XLogP -18.41
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

Bioactivity Comments
This drug attaches non-specifically to proteins in ulcerated tissue (such as albumin and fibrinogen). Acid-induced cross-linking creates a viscous, paste-like material which acts as a protective barrier. This drug therefore has no 'primary' molecular target.