sucralfate

Ligand id: 7055

Name: sucralfate

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 51
Hydrogen bond donors 16
Rotatable bonds 36
Topological polar surface area 839.21
Molecular weight 1447.59
XLogP -18.41
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat active duodenal ulcers not caused by use of NSAIDs. The drug aids healing only, and does not prevent new ulcer formation.
Mechanism Of Action and Pharmacodynamic Effects
In the acidic conditions of the duodenum and stomach, the drug forms a viscous, impenetrable layer over the surface of active ulcer sites and protects them from corrosive substances such as stomach acid, enzymes, and bile salts.
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