inamrinone

Ligand id: 7202

Name: inamrinone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 72.03
Molecular weight 187.07
XLogP 0.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
phosphodiesterase 3A Inhibitor Inhibition 4.8 pIC50 - 1
pIC50 4.8 (IC50 1.6x10-5 M) [1]
Description: Inhibition of PDE3 purified from human platelets, and therefore assumed to be the PDE3A subtype.
phosphodiesterase 3B Inhibitor Inhibition 4.5 pIC50 - 2
pIC50 4.5 (IC50 3.12x10-5 M) [2]