ibudilast

Ligand id: 7399

Name: ibudilast

Structure and Physico-chemical Properties

2D Structure

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Ibudilast is predominantly a PDE4 inhibitor [2].
Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
phosphodiesterase 4A Inhibitor Inhibition 7.3 pIC50 - 2
pIC50 7.3 (IC50 5.4x10-8 M) [2]
phosphodiesterase 4B Inhibitor Inhibition 7.2 pIC50 - 2
pIC50 7.2 (IC50 6.5x10-8 M) [2]
phosphodiesterase 4C Inhibitor Inhibition 6.6 pIC50 - 2
pIC50 6.6 (IC50 2.39x10-7 M) [2]
phosphodiesterase 5A Inhibitor Inhibition 4.0 pIC50 - 1
pIC50 4.0 (IC50 1.03x10-4 M) [1]
phosphodiesterase 3A Inhibitor Inhibition 3.5 pIC50 - 1
pIC50 3.5 (IC50 2.99x10-4 M) [1]