birinapant

Ligand id: 7432

Name: birinapant

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 14
Hydrogen bond donors 8
Rotatable bonds 19
Topological polar surface area 194.92
Molecular weight 806.43
XLogP 2.47
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human other protein targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
baculoviral IAP repeat containing 2 Antagonist Antagonist >9.0 pKd - 1
pKd >9.0 (Kd <1x10-9 M) [1]
X-linked inhibitor of apoptosis Antagonist Antagonist 7.3 pKd - 1
pKd 7.3 (Kd 4.5x10-8 M) [1]