avanafil

Ligand id: 7448

Name: avanafil

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: avanafil

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 125.39
Molecular weight 483.18
XLogP 2.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Most of the research into the pharmacology of this drug appears to have been carried out in dogs. We have been unable to find publicly available bioactivity for avanafil in relation to human PDE5 to substantiate its clinical MMOA. Therefore, we have not tagged a primary target for this drug.