clorazepate

Ligand id: 7548

Name: clorazepate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 78.76
Molecular weight 314.05
XLogP 4.33
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Clorazepate positively modulates the activity of GABAA receptors expressed in Xenopus oocytes injected with chick embryo mRNA, with a Ki of 390nM [1]. There appears to be no publicly available bioactivity data for this drug at its human molecular target so we have not mapped a primary drug target in this instance.