clorazepate

Ligand id: 7548

Name: clorazepate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 78.76
Molecular weight 314.05
XLogP 4.33
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used short term to provide symptomatic relief of anxiety (Canada, France, Japan) and to treat alcohol withdrawal (Canada, France).
Mechanism Of Action and Pharmacodynamic Effects
Clorazepate is a GABAA receptor positive allosteric modulator, which interacts with the benzodiazepine allosteric site [1].
External links