Ligand id: 7597

Name: pralidoxime

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 36.47
Molecular weight 137.07
XLogP 1.81
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
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Target Sp. Type Action Affinity Units Concentration range (M) Reference
acetylcholinesterase (Cartwright blood group) Hs Inhibitor Inhibition 3.1 pIC50 - 1
pIC50 3.1 (IC50 8.78x10-4 M) [1]
Description: Inhibition of human recombinant AChE by modified Ellman's method.