pralidoxime

Ligand id: 7597

Name: pralidoxime

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 36.47
Molecular weight 137.07
XLogP 1.81
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
acetylcholinesterase (Cartwright blood group) Inhibitor Inhibition 3.1 pIC50 - 1
pIC50 3.1 (IC50 8.78x10-4 M) [1]
Description: Inhibition of human recombinant AChE by modified Ellman's method.