Ligand id: 7616

Name: phenazopyridine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 89.65
Molecular weight 213.1
XLogP 3.43
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Phenazopyridine significantly and dose-dependently increased bladder compliance in experiments using rats. This was reportedly due to inhibition of Aδ fibres in the bladder [1]. However, as the precise molecular target(s) of this drug have not been fully resolved, we have not tagged a primary drug target in this case.