Ligand id: 7999

Name: sarilumab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
Interleukin-6 receptor, α subunit Hs Antibody Binding 10.6 – 11.1 pKd - 3
pKd 10.6 – 11.1 (Kd 2.3x10-11 – 9x10-12 M) [3]
Description: Dissociation equilibrium constant calculated using two different assay methods (kinetic vs. equilibrium/solution)