Ligand id: 7999

Name: sarilumab

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human catalytic receptors
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Target Type Action Affinity Units Concentration range (M) Reference
Interleukin-6 receptor, α subunit Antibody Binding 10.6 – 11.1 pKd - 3
pKd 10.6 – 11.1 (Kd 2.3x10-11 – 9x10-12 M) [3]
Description: Dissociation equilibrium constant calculated using two different assay methods (kinetic vs. equilibrium/solution)