Ligand id: 8078

Name: secukinumab

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Selectivity at Human ligand targets
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Target Type Action Affinity Units Concentration range (M) Reference
IL-17A Antibody Binding 9.9 pKd - 2
pKd 9.9 (Kd 1.22x10-10 M) [2]
Description: Binding affinity for recombinant human IL-17
IL-17A Antibody Binding 8.7 pIC50 - 2
pIC50 8.7 (IC50 2.1x10-9 M) [2]
Description: Inhibition of IL-17-induced IL-6 production by human dermal fibroblasts.