Ligand id: 8078

Name: secukinumab

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
IL-17A Hs Antibody Binding 9.9 pKd - 2
pKd 9.9 (Kd 1.22x10-10 M) [2]
Description: Binding affinity for recombinant human IL-17
IL-17A Hs Antibody Binding 8.7 pIC50 - 2
pIC50 8.7 (IC50 2.1x10-9 M) [2]
Description: Inhibition of IL-17-induced IL-6 production by human dermal fibroblasts.